UD Biomedical Engineering
5 Innovation Way
Suite 200, Room 134
Newark, DE 19711
Phone: (302) 831-4836
Postdoctoral Fellow, Department of Chemical & Biological Engineering, Princeton University
Postdoctoral Fellow, Sibley School of Mechanical & Aerospace Engineering, Cornell University
Ph.D. in Biomedical Engineering, Cornell University
B.S. in Mechanical Engineering, WPI
The Gleghorn Lab is an interdisciplinary research group that is focused on understanding how cells assemble into functional tissues. We develop and use microfluidic and microfabrication technologies to determine how cells behave and communicate within multicellular populations to form complex 3D tissues and organs. In particular, we use developing organs, microfabricated 3D organotypic culture models, quantitative analysis, and computational methods to investigate the biophysical forces and chemical signals that drive tissue growth, homeostasis, and disease. Our work integrates fundamental engineering, molecular, cell, and developmental biology, and materials science to delineate cellular behaviors and interactions at the cellular, tissue, and organ length scales. The long-term goals of this research are to develop techniques to engineer physiologically relevant 3D culture systems with well-defined structure, flows, and cell-cell interactions to study tissue-scale biology and disease. These techniques in combination with what we learn in our studies of the native cellular behaviors and interactions in the embryo will be used to define new therapeutic approaches for regenerative medicine.
If you have an interest in working at the interface of engineering, biology, and medicine to investigate cellular communication within developing organs and multicellular engineered systems, please contact Dr. Gleghorn for more information.