The Protein Production Core (PPC) Facility is a core laboratory that serves academic investigators in Delaware. The PPC is part of shared core facilities supported by the Center of Biomedical Research Excellence (COBRE) in Membrane Protein Production and Characterization at the University of Delaware. The PPC has modern instrumentation for large scale expression, purification and characterization of prokaryotic and eukaryotic proteins for investigators and researchers. The core supports the production of proteins in quantities suitable for structural studies (X-ray and NMR) and functional studies (biological or catalytic). The PPC also has state-of-the-art analytical ultracentrifuge for studying macromolecule interactions.